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Protonix, like all acid suppressants, can sometimes interfere with vitamin b-12 absorption, which means that with regular use, a person may suffer from vitamin b-12 deficiency.
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Metabolic/Nutritionalelevated CPKcreatine phosphokinasegeneralized edemaelevated triglyceridesliver function tests abnormal.
Pantoprazole sodium may produce false-positive urine screen for THCtetrahydrocannabinolsee Drug Interactions7
Literature suggests that concomitant use of PPIs with methotrexateprimarily at high dosesee methotrexate prescribing informationmay elevate and prolong serum levels of methotrexate and/or its metabolitepossibly Zebeta without a prescription leading to methotrexate toxicitiesIn high-dose methotrexate administrationa temporary withdrawal of the PPI may be considered in some patientssee Drug Interactions7
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