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Immune reconstitution syndrome has been reported in patients treated with combination antiretroviral therapyincluding lamivudineDuring the initial phase of HIV treatmentpatients whose immune system responds to antiretroviral therapy may develop an inflammatory response to indolent or residual opportunistic infectionssuch as progressive multifocal leukoencephalopathyPMLmycobacterium avium complexMACcytomegalovirusCMVPneumocystis carinii pneumoniaPCPor tuberculosisTBwhich may necessitate further evaluation and Can lexapro treat bipolar disorder treatmentIn additionautoimmune diseaseincluding GravesdiseaseGuillain-Barre syndromeand polymyositismay also develop in the setting of immune reconstitutionthe time to onset is variable and may occur months after treatment initiation.

Tell your doctor right away if any of these rare but very serious side effects occurdeep/rapid breathingdrowsinesstingling/numbness in hands or feet.

Lactic acidosis and severe hepatomegaly with steatosisincluding fatal caseshave been reported with the use of nucleoside analogues and other antiretroviralsA majority of these cases have been in womenObesity and prolonged nucleoside exposure may be risk factorsMost of these reports have described patients receiving nucleoside analogues for treatment of HIV infectionbut there have been reports of lactic acidosis in patients receiving lamivudine for hepatitis BCaution should be exercised when administering Epivir-HBV to any patient with known risk factors for liver diseasehowevercases also have been reported in patients with no known risk factorsTreatment with Epivir-HBV should be suspended in any patient who develops clinical or laboratory findings suggestive of lactic acidosis or pronounced hepatotoxicitywhich may include hepatomegaly and steatosis even in the absence of marked transaminase elevations

Lactic acid buildup in the bloodlactic acidosisand sometimes fatal liver disease have occurred with the use of lamivudine-HBVused both alone and in combination with other drugs for treating human immunodeficiency virusHIVinfection.

There is no information available regarding the effects of the drug on the breastfed infant or on milk production.

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epivir and epivir-hbv are brand names for lamivudine.